48 Recovery and the Immune System with Oliver Neubauer, PhD
/Think the immune system just helps to keep us from getting sick or to recover from illness? Think again...
Here are links from Dr. Neubauer to a selection of the papers that we discussed.
- Our EJAP paper on the acute systemic inflammatory response and muscle damage following an Ironman triathlon. As we investigated leukocyte counts, cortisol, testosterone, inflammation and muscle damage markers immediately, 1, 5 and 19 d after the race in a large cohort of athletes (n=42) we were able to also document the resolution of these responses. FULL PAPER HERE
- Our MSSE paper on oxidative stress responses in the same cohort of athletes. Addressing previous health concerns related to ultra-endurance exercise, these data suggest that there are no indications of persistent oxidative stress in response to an Ironman triathlon. FULL PAPER HERE
- A book chapter (co-authored by Christina Yfanti) on the (remaining) hot topic on antioxidants in sports nutrition, particularly addressing the question regarding requirements of vitamins C and E during exercise training FULL CHAPTER HERE
- Our JAP paper on the so called transcriptome, i.e., global gene expression responses in blood neutrophils during recovery from 2 h of cycling and running in trained males. It shows the transcriptional regulation underlying the neutrophils responses to prolonged, intense exercise, and how they appear to counter-regulate their “own” initial pro-inflammatory response FULL PAPER HERE
- Our JAP paper on the time-course dependent changes in the transcriptome of skeletal muscle during recovery from 2 h of cycling and running. Investigating these responses 3, 48 and 96 h after exercise, these data suggest pronounced interactions between the muscle and immune cells and that muscle recovery is still incomplete 96 h after the initiating bout of exercise ended. FULL PAPER HERE